منتدى عالم الأسرة والمجتمع - عرض مشاركة واحدة - مصاب بعدة امراض فهل يمكن اجراء عملية نقل كلية له ؟
عرض مشاركة واحدة
قديم 06-04-2010, 04:37 PM
  #6
عندي حلم
عضو جديد
تاريخ التسجيل: Mar 2010
المشاركات: 33
عندي حلم غير متصل  
أخي unbelievable
أنا لم أحدد سبب الفشل الكلوي وإنما وجهت سؤالي للاخت .. هل فيروس الكبد وصل للمرحله المزمنه والذي يترتيب عليه تليف الكبد أم لا
لانه لا السكر ولا الضغط ولا حتى سن ال 60 من الموانع الرئيسيه لنقل الكليه
وحتى التهاب الكبد الوبائي في مراحله المبكره ليس من الموانع الرئيسيه بل relative contraindication
في حالة hepatorenal syndrome لو تمت الموافقه على عملية الزراعه .. فما يتم زرعه هو الكبد فقط .. وليس الكليه لان الكليه سليمه تماما all glomerular and tubular functions are spared >>and you can confirm that by biopsy

أنقل إليك هذه الاحصائيه عن أعمار المنتظرين لعملية الزارعه في الولايات المتحده

Age

The proportion of patients either waiting for a kidney transplant or receiving a kidney transplant according to age is as follows:5


Open table in new window

Age, Years Wait List, % Transplant, %
0-19 2.8 3.7
20-39 31.2 33.6
40-59 15.0 13.0
60-70 39.5 37.2


وهنا أنقل إليك دراسة أعدتها جامعة ميريلاند (لاسف لا أملك رقم الدراسه أو تاريخها )

Multiple intercurrent conditions
a. Multiple medical problems, which individually may not contraindicate transplantation, could produce an aggregate effect in a transplant candidate that would pose an unacceptable risk for transplantation. An example would be an elderly patient (over age 65), with serious cardiac disease, perhaps with marked obesity, diabetes, or an extensive smoking history

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Recipient Contraindications to Kidney Transplantation
Absolute
The following are conditions relating to the kidney recipient candidate that constitute absolute contraindications to kidney transplantation. As such, they prevent a transplant from b**** done until the condition is resolved.
1) Positive CDC-AHG crossmatch
a. A positive CDC-AHG crossmatch between the donor and recipient is a contraindication to transplantation because of the increased risk of hyperacute rejection. Consideration should be given to a pre-transplant conditioning protocol (involving recipient plasmapheresis), which could convert the CDC-AHG crossmatch to negative, and eliminate this contraindication.
2) Non-compliance
a. Convincing evidence that the recipient will be non-compliant with the recommendations of the transplant team afterwards is a contraindication because non-compliance will cause failure of the kidney from rejection. Patients with a history of non-compliance, or substance abuse, should be carefully screened before transplant.
3) Serious active infection
a. Postoperative immunosuppressants would make it more difficult to eradicate a serious active infection that is present at the time of transplant, and could potentially threaten the recipient’s ability to recover from the procedure. Therefore, active serious infection is a contraindication to transplantation. Examples include infections such as peritonitis, osteomyelitis, pneumonia, hemodialysis graft infection, tuberculosis, etc.
4) Active malignancy under treatment
a. Patients with an active malignancy still under treatment are excluded from transplantation until such time as it is very unlikely that there is any residual cancer, and the patient is thought to be cured. The time interval between treatment and transplantation depends on the type, stage, and grade of cancer, and the type of treatment given.
5) Inadequate financial resources
a. Patients with inadequate or poorly defined financial resources may be unable to obtain the expensive medications and treatments needed to prevent failure of the transplant. If there is an unacceptably high risk of premature graft failure on this basis, the transplant should not be performed.
6) Certain severe, uncontrollable medical problems
a. Certain medical problems are contraindications when they are severe, and not amenable to improvement. In this case, the condition could sharply limit the recipient’s life expectancy regardless of whether a transplant is done, and would reduce the chances of survival after transplant surgery. Examples include severe, uncontrollable heart disease, lung disease, liver disease, and mental illness.
7) Pregnancy
a. Pregnant women are not transplant candidates. A suitable period of time should elapse after delivery before transplantation.